Vanoglio F, Bernocchi P, Mulè C, Garofali F, Mora C, Taveggia G, Scalvini S,
Luisa A. Feasibility and efficacy of a robotic device for hand rehabilitation in hemiplegic stroke patients:
a randomized pilot controlled study. Clin Rehabil. 2017

Gloreha glove is feasible and effective in recovering fine
manual dexterity and strength andreducing arm disability
in sub-acute hemiplegic patients. [...]
Patients in the treatment group significantly improved
the motor function of the paretic upper limb (Motricity Index),
their coordination and mono-manual dexterity (Nine Hole Peg Test)
and strength (Grip and Pinch) in contrast to controls,
and the cost savings was considerable.

Robot-assisted training using the Gloreha device
demonstrated beneficial effects on body structure and function, including upper extremity motor function, brachioradialis muscle recruitment, and coordination, in children with Cerebral Palsy. The beneficial effects were maintained 1 month after training termination.

Kuo FL, Lee HC, Hsiao HY, Lin JC. Robotic-assisted hand therapy for improvement of hand function in children with cerebral palsy: a case series study. Eur J Phys Rehabil Med. 2020

According to recent literature, the hand rehabilitation program with Gloreha provides an intensive, repetitive, functional, taskoriented, specific, and customizable treatment. [...] The exercises with devices work on plasticity in the central nervous system due to the neuromotor, audiovisual feedback: the multisensory action-observation system enables patients to re- learn impaired motor function through the activation of internal action-related representations. [...] Our results showed a great improvement on the ADL and positively marked functional recovery of motor function. An important aspect of our study was the association of robotic therapy with the traditional rehabilitation-based approach of physiotherapy and OT to provide more full and intensive sessions to improve the outcome

Milia P, Peccini MC, De Salvo F, Sfaldaroli A, Grelli C, Lucchesi G, et al. Rehabilitation with robotic glove (Gloreha) in poststroke patients. Digit Med 2019

MAIN SCIENTIFIC PUBLICATIONS:

Hoidekrová K., Rogalewicz V., Jahromi M. M., Sobrova M., Pavlů D.
Effect of bimanual sensor glove and unimanual robot-assisted therapy for upper limb function after stroke
Cesk Slov Neurol N 2024; 87(2): 114-121
Vanoglio F, Comini L, Gaiani M, Bonometti GP, Luisa A, Bernocchi P.
A Sensor-Based Upper Limb Treatment in Hemiplegic Patients: Results from a Randomized Pilot Study.
Sensors (Basel). 2024 Apr 17;24(8):2574. doi: 10.3390/s24082574. PMID: 38676190; PMCID: PMC11054364.
Bressi F, Cricenti L, Bravi M, Pannunzio F, Cordella F, Lapresa M, Miccinilli S, Santacaterina F, Zollo L, Sterzi S, Campagnola B.
Treatment of the Paretic Hand with a Robotic Glove Combined with Physiotherapy in a Patient Suffering from Traumatic Tetraparesis: A Case Report.
Sensors (Basel). 2023 Mar 27;23(7):3484. doi: 10.3390/s23073484. PMID: 37050544; PMCID: PMC10099243.
Bressi, F.; Santacaterina, F.; Cricenti, L.; Campagnola, B.; Nasto, F.; Assenza, C.; Morelli, D.; Cordella, F.; Lapresa, M.; Zollo, L.; et al.
“Robotic-Assisted Hand Therapy with Gloreha Sinfonia for the Improvement of Hand Function after Pediatric Stroke: A Case Report”
Appl. Sci. 2022, 12, 4206
Andrea Crema, Michela Bassolino, Eleonora Guanziroli, Maria Colombo, Olaf Blanke, Andrea Serino, Silvestro Micera, Franco Molteni
“Neuromuscular electrical stimulation restores upper limb sensory-motor functions and body representations in chronic stroke survivors”
Med (N Y). 2022 Jan 14;3(1):58-74.e10
Lee HC, Kuo FL, Lin YN, Liou TH, Lin JC, Huang SW.
“Effects of Robot-Assisted Rehabilitation on Hand Function of People With Stroke: A Randomized, Crossover-Controlled, Assessor-Blinded Study”
Am J Occup Ther. 2021 Jan-Feb;75(1):7501205020p1-7501205020p11. doi: 10.5014/ajot.2021.038232. PMID: 33399050
Kuo FL, Lee HC, Hsiao HY, Lin JC
“Robotic-assisted hand therapy for improvement of hand function in children with cerebral palsy: a case series study”
European Journal of Physical and Rehabilitation Medicine, 2020 Jan 14
Miccinilli S, Bravi M, Foti C, Morrone M, Maselli M, Santacaterina F, Scotto Di Luzio F, Zollo L, Sterzi S, Bressi F.
“Robotic hand treatment of patients affected by chronic stroke: a monocentric longitudinal pilot study”
J Biol Regul Homeost Agents. 2020 Sep-Oct;34(5 Suppl. 3):79-86. Technology in Medicine. PMID: 33386037
Fabio Vanoglio
“Guanto robotico Gloreha Sinfonia: review degli studi recenti”
Il Fisioterapista, Gennaio – Febbraio 2020
Paolo Milia, Maria Cristina Peccini, Federico De Salvo, Alice Sfaldaroli, Chiara Grelli, Lucchesi Giorgia, Nora Sadauskas, Catia Rossi, Marco Caserio, Mario Bigazzi
“Rehabilitation with robotic glove (Gloreha) in poststroke patients”
Digital Medicine Journal, 2019
K. Hoidekrova, O. Svestkova
“Effect of Bimanual robotic assisted therapy to perform activities of daily living in patients after acquired brain injury: pilot study”
V. Kladruby Symposium on Interdisciplinary Neurorehabilitation, 2018
Miccinilli S, Bravi M, Santacaterina F, Simonetti D, Scotto Di Luzio F, Morrone M, Milighetti S, Bressi F, Sterzi S
Robotic treatment of the hand according to impairment severity in patients affected by chronic stroke: a monocentric longitudinal study
Presented at the 12th ISPRM Congress (2018)
D. Quaglia, M. Gasperi, R. Coser, G. Grisenti, M. Scartozzi, E. Girardi, N. Mazzini
“Robotic rehabilitation effect on upper limb recovery in post-acute stroke”
Gait & Posture, October 2018
Massimiliano Gobbo, Paolo Gaffurini, Laura Vacchi, Sara Lazzarini, Jorge Villafane, Claudio Orizio, Stefano Negrini and Luciano Bissolotti
“Hand Passive Mobilization Performed with Robotic Assistance: Acute Effects on Upper Limb Perfusion and Spasticity in Stroke Survivors”
Hindawi BioMed Research International Volume 2017
Jorge H. Villafañe, Giovanni Taveggia, Silvia Galeri, Luciano Bissolotti, Chiara Mulè, Grace Imperio, Kristin Valdes, Alberto Borboni, and Stefano Negrini
“Efficacy of Short-Term Robot-Assisted Rehabilitation in Patients With Hand Paralysis After Stroke: A Randomized Clinical Trial”
American Association for Hand Surgery 2017
Konečný P., Tarasová M., Kubíková J., Vernerová M.
“Robotická rehabilitace spasticity ruky” (Robotic Rehabilitation of the Hand Spasticity)
Rehabilitace a fyzikální lékařství 2017, 24, č. 1
Jorge Hugo Villafañe, Kristin Valdes, Grace Imperio, Alberto Borboni, Raquel Cantero-Téllez, Silvia Galeri, Stefano Negrini,
“Neural manual vs. robotic assisted mobilization to improve motion and reduce pain hypersensitivity in hand osteoarthritis: study protocol for a randomized controlled trial”
J. Phys. Ther. Sci. 29: 801–806, 2017
Jakub Petioky, Luciano Bissolotti, Benedetta Chioda, Kristyna Hoidekrova
“Effectiveness of upper limb training with Gloreha for stroke survivors with moderate to severe upper limb disability: a randomized controlled trial, preliminary results”
Presented at 3rd European Stroke Organization Conference, 2017
Jakub Pětioký, Jana Krásová, Petra Mikulenková, Markéta Dojavová
“Robotic Glove with virtual reality biofeedback in spasticity management on acute and chronic patients with spastic hand paresis: impact on goal oriented functional therapy and routine mass therapy”
Presented at the 20th ESPRM Congress (2016)
Maria Giulia Montecchi, Francesca Magnanini, Simone Tettamanzi, Barbara Volta, Erica Pederzini, Francesco Lombardi
“Is passive mobilization robot-assisted therapy effective in upper limb motor recovery in patient with acquired Brain Injury? A randomized crossover trial”
Int J Phys Ther Rehab 2016, 2: 114
Luciano Bissolotti, Jorge Hugo Villafane, Paolo Gaffurini, Claudio Orizio, Kristin Valdes, Stefano Negrini
“Changes in skeletal muscle perfusion and spasticity in patient with poststroke hemiparesis treated by robotic assistance (Gloreha) of the hand”
Phys. Ther. Sci. 28: 769-773 2016
Fabio Vanoglio, Palmira Bernocchi, Chiara Mulè, Francesca Garofali, Chiara Mora, Giovanni Taveggia, Simonetta Scalvini and Alberto Luisa
“Feasibility and efficacy of a robotic device for hand rehabilitation in hemiplegic stroke patients: a randomized pilot controlled study”
Clin Rehabil. 2016 Apr 7
Alberto Borboni, Jorge H. Villafañe, Chiara Mulè, Kristin Valdes, Rodolfo Faglia, Giovanni Taveggia, Stefano Negrini,
“Robot-Assisted Rehabilitation of Hand Paralysis After Stroke Reduces Wrist Edema and Pain: A Prospective Clinical Trial”
J Manipulative Physiol Ther. 2016 Nov 12
Rodigari A., Zancan A., Jedrychowska I., Springhetti I.
“Effectiveness of the treatment of hemiplegic patient’s hand with Gloreha robotic rehabilitation glove: preliminary results”
Proceedings of the 42nd National Congress of the Italian Society of Physical and Rehabilitative Medicine, Edizioni Minerva Medica, 2015.
Gastaldo M., Azzolin I., Campagnoli M., Filipovic I., Pasquero F., Desilvestri M., Capacchione P., Massazza G.
“Robot-assisted therapy integrated with virtual reality for rehabilitation of hand function after stroke: a clinical case study”
Presented at the 9th ISPRM Congress (2015)
Valentina Varalta, Alessandro Picelli, Cristina Fonte, Giulia Montemezzi, Elisabetta La Marchina, Nicola Smania
“Effects of contralesional robot-assisted hand training in patients with unilateral spatial neglect following stroke: a case series study”
Journal of NeuroEngineering and Rehabilitation 2014, 11:160

FURTHER STUDIES:

Pedersini, P., Valdes, K., Cantero-Tellez, R., Cleland, J.A., Bishop, M.D. and Villafañe, J.H.
“Effects of Neurodynamic Mobilizations on Pain Hypersensitivity in Patients With Hand Osteoarthritis Compared to Robotic Assisted Mobilization: A Randomized Controlled Trial” Arthritis Care Res, 73: 232-239, 2021
Giancarlo Mercurio
“Mano Robotica: Gloreha Sinfonia 2.0 – Dati preliminari”
NEU – Giugno 2020
Cordella F, Scotto Di Luzio F, Bravi M, Santacaterina F, Bressi F, Zollo L.
Hand motion analysis during robot-aided rehabilitation in chronic stroke.
J Biol Regul Homeost Agents. 2020 Sep-Oct;34(5 Suppl. 3):45-52. Technology in Medicine. PMID: 33386033
Paola Torretta, Lucia Anzivino, Giancarlo Mercurio
“Mi Riabilita: L’utilizzo di una mano 2.0 per la riabilitazione alle persone assistite con patologia neuromotorie”
NEU – Dicembre 2019
L. Bissolotti
“Leap motion and serious games in Parkinson’s disease”
V. Kladruby Symposium on Interdisciplinary Neurorehabilitation, 2018
Zenorini Andrea, Chiari Sonia, Zuccher Paola, Bissolotti Luciano, Migliarini Daniele, Turla Elena, Spinella Flavio, Gaffurini Paolo
“Effetti percepiti durante riabilitazione robotizzata dell’arto superiore con Gloreha Sinfonia Idrogenet® in pazienti affetti da ictus cerebri”
MR – Giornale Italiano di Medicina Riabilitativa, Vol. 31 – Suppl 1 al N.3
Palmira Bernocchi, Chiara Mulè, Fabio Vanoglio, Giovanni Taveggia, Alberto Luisa, Simonetta Scalvini
“Home-based hand rehabilitation with a robotic glove in hemiplegic patients after stroke: a pilot feasibility study”
Topics in Stroke Rehabilitation, 2017, DOI: 10.1080/10749357.2017.1389021
Fabio Guerini, Martina Callera, Andrea Campanini, Luciano Bissolotti, Giuseppe Bellelli, Marco Trabucchi
“La riabilitazione robotizzata dell’arto superiore in pazienti affetti da esiti di ictus in fase cronica: un confronto con la terapia convenzionale”
Presented at the 61st National Congress of the Italian Society of Gerontology and Geriatrics, 2017
Petioky J., Bissolotti L., Hoidekrova K., Chioda B.
“Efficacy of robotic and Action-Observation therapy for upper limb rehabilitation after stroke. Preliminary results of a multicenter trial”
Presented at the 4th European Congress of Neurorehabilitation, 2017
Bissolotti Luciano, Petioky Jakub, Hoidekrová Kristýna, Zuccher Paola, Zenorini Andrea, Migliarini Daniele, Turla Elena, Gaffurini Paolo
“Effetti della riabilitazione robotizzata dell’arto superiore con Gloreha Idrogenet® in pazienti affetti da ictus con disabilità da moderata a grave severità: risultati preliminari”
MR – Giornale Italiano di Medicina Riabilitativa, Vol. 31 – Suppl 1 al N.3, 2017
Borboni A., Mor M., Faglia R.
“Gloreha – Hand Robotic Rehabilitation: Design, Mechanical Model, and Experiments”
J. Dyn. Sys., Meas., Control 138(11), 111003 (Jul 11, 2016)
Bissolotti L., Gobbo M., Gaffurini P., Orizio C.,
“The perceived effectiveness after Gloreha treatment in patients with stroke: a comparison with physical therapists judgment”
Presented at the 9th World Congress of the International Society of Physical and Rehabilitation Medicine, 2015.
Vanoglio F., Mulè C., Bernocchi P., Salvi L., Galli T., Luisa A., Taveggia G.,
“Gloreha project for telerehabilitation: a home rehabilitation device for patients with hand deficits”
Presented at 42nd National Congress of the Italian Society of Physical and Rehabilitative Medicine, 2014.
Bissolotti L.,
“Robotic rehabilitation of the upper limb after stroke: analysis of peripheral vascular adaptations during Gloreha treatment”
Presented at the XIV Congress of Italian Society of Neurorehabilitation, 2014.
Parrinello I., Faletti S., Santus G.
“Use of a continuous passive motion device for hand rehabilitation: clinical trial on neurological patients”
Presented at the 41st National Congress of Italian Society of Medicine and Physical Rehabilitation, 2013.
Stagno D., Baricich A., Invernizzi M., Grana E., Cisari C.
“Use of a robotic device in the rehabilitation treatment after botulinum toxin (type A) injection on spastic upper limb after stroke. Pilot study”
Presented at the XIII Congress of Italian Society of Neurorehabilitation, 2013.
Molteni F., Mulè C., Caimmi M., Taveggia G., Missud S., Bianchi P.
“Use of continuous passive motion device for the hand on post-stroke patients: pilot study”
Presented at the 39th National Congress of Italian Society of Medicine and Physical Rehabilitation, 2011.

MAIN SCIENTIFIC PUBLICATIONS:

FURTHER STUDIES:

Gloreha Now Part of BTL Robotics!